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Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma

Multiple myeloma (MM) and its precursors monoclonal gammopathy of undetermined significance (MGUS) and smoldering myeloma (SMM) are 2–3 times more common in African Americans (AA) than European Americans (EA). Although epigenetic changes are well recognized in the context of myeloma cell biology, th...

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Detalles Bibliográficos
Autores principales: Chiu, Brian C.-H., Zhang, Zhou, Derman, Benjamin A., Karpus, Jason, Luo, Liangzhi, Zhang, Sheng, Langerman, Spencer S., Sukhanova, Madina, Bhatti, Parveen, Jakubowiak, Andrzej, He, Chuan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380317/
https://www.ncbi.nlm.nih.gov/pubmed/35974364
http://dx.doi.org/10.1186/s13045-022-01327-y