Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis

BACKGROUND: B-cell acute lymphoblastic leukemia (B-ALL) comprises over 85% of all acute lymphoblastic leukemia (ALL) cases and is the most common childhood malignancy. Although the 5 year overall survival of patients with B-ALL exceeds 90%, patients with relapsed or refractory B-ALL may suffer from...

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Detalles Bibliográficos
Autores principales: Huang, Lan, An, Xizhou, Zhu, Yao, Zhang, Kainan, Xiao, Li, Yao, Xinyuan, Zeng, Xing, Liang, Shaoyan, Yu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380321/
https://www.ncbi.nlm.nih.gov/pubmed/35974411
http://dx.doi.org/10.1186/s12964-022-00935-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380321/
https://www.ncbi.nlm.nih.gov/pubmed/35974411
http://dx.doi.org/10.1186/s12964-022-00935-y

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