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Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis

BACKGROUND: B-cell acute lymphoblastic leukemia (B-ALL) comprises over 85% of all acute lymphoblastic leukemia (ALL) cases and is the most common childhood malignancy. Although the 5 year overall survival of patients with B-ALL exceeds 90%, patients with relapsed or refractory B-ALL may suffer from...

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Detalles Bibliográficos
Autores principales:	Huang, Lan, An, Xizhou, Zhu, Yao, Zhang, Kainan, Xiao, Li, Yao, Xinyuan, Zeng, Xing, Liang, Shaoyan, Yu, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380321/ https://www.ncbi.nlm.nih.gov/pubmed/35974411 http://dx.doi.org/10.1186/s12964-022-00935-y

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