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Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists despite anti-TNF treatment

BACKGROUND: Accumulating evidence supports the role of monocytes and neutrophils in radiographic axSpA (r-axSpA). Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a growth factor for both leukocyte lineages and a pro-inflammatory cytokine activating myeloid cells and promoting osteoclast...

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Detalles Bibliográficos
Autores principales: Papagoras, Charalampos, Tsiami, Styliani, Chrysanthopoulou, Akrivi, Mitroulis, Ioannis, Baraliakos, Xenofon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380324/
https://www.ncbi.nlm.nih.gov/pubmed/35974380
http://dx.doi.org/10.1186/s13075-022-02888-6