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Prioritization of cancer driver gene with prize-collecting steiner tree by introducing an edge weighted strategy in the personalized gene interaction network

BACKGROUND: Cancer is a heterogeneous disease in which tumor genes cooperate as well as adapt and evolve to the changing conditions for individual patients. It is a meaningful task to discover the personalized cancer driver genes that can provide diagnosis and target drug for individual patients. Ho...

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Detalles Bibliográficos
Autores principales: Zhang, Shao-Wu, Wang, Zhen-Nan, Li, Yan, Guo, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380343/
https://www.ncbi.nlm.nih.gov/pubmed/35974311
http://dx.doi.org/10.1186/s12859-022-04802-y