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Prioritization of cancer driver gene with prize-collecting steiner tree by introducing an edge weighted strategy in the personalized gene interaction network
BACKGROUND: Cancer is a heterogeneous disease in which tumor genes cooperate as well as adapt and evolve to the changing conditions for individual patients. It is a meaningful task to discover the personalized cancer driver genes that can provide diagnosis and target drug for individual patients. Ho...
Autores principales: | Zhang, Shao-Wu, Wang, Zhen-Nan, Li, Yan, Guo, Wei-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380343/ https://www.ncbi.nlm.nih.gov/pubmed/35974311 http://dx.doi.org/10.1186/s12859-022-04802-y |
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