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Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice
Alzheimer's disease (AD) is characterized by intracerebral accumulations of extracellular amyloid-β (Aβ) plaques and intracellular tau pathology that spread in the brain. Three types of tau lesions occur in the form of neuropil threads, neurofibrillary tangles, and neuritic plaques i.e. tau agg...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380345/ https://www.ncbi.nlm.nih.gov/pubmed/35974399 http://dx.doi.org/10.1186/s40478-022-01410-y |