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CellRegMap: a statistical framework for mapping context‐specific regulatory variants using scRNA‐seq

Single‐cell RNA sequencing (scRNA‐seq) enables characterizing the cellular heterogeneity in human tissues. Recent technological advances have enabled the first population‐scale scRNA‐seq studies in hundreds of individuals, allowing to assay genetic effects with single‐cell resolution. However, exist...

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Detalles Bibliográficos
Autores principales: Cuomo, Anna S E, Heinen, Tobias, Vagiaki, Danai, Horta, Danilo, Marioni, John C, Stegle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380406/
https://www.ncbi.nlm.nih.gov/pubmed/35972065
http://dx.doi.org/10.15252/msb.202110663