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LDL cholesterol is associated with higher AD neuropathology burden independent of APOE

OBJECTIVE: APOE is a strong risk factor for Alzheimer’s disease (AD) and associated with higher low-density lipoprotein cholesterol (LDL-C) levels. Moreover, LDL-C is associated with the development of clinically ascertained AD; however, whether this association is present with the underlying neurop...

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Detalles Bibliográficos
Autores principales: Wingo, Aliza P, Vattathil, Selina M, Liu, Jiaqi, Fan, Wen, Cutler, David J, Levey, Allan I, Schneider, Julie A, Bennett, David A, Wingo, Thomas S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380478/
https://www.ncbi.nlm.nih.gov/pubmed/35772923
http://dx.doi.org/10.1136/jnnp-2021-328164