Functional and Metagenomic Evaluation of Ibezapolstat for Early Evaluation of Anti-Recurrence Effects in Clostridioides difficile Infection

Reduction of Clostridioides difficile infection (CDI) recurrence is an essential endpoint for CDI-directed antibiotic development that is often not evaluated until Phase III trials. The purpose of this project was to use a functional and metagenomic approach to predict the potential anti-CDI recurre...

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Detalles Bibliográficos
Autores principales: McPherson, Jacob, Hu, Chenlin, Begum, Khurshida, Wang, Weiqun, Lancaster, Chris, Gonzales-Luna, Anne J., Loveall, Caroline, Silverman, Michael H., Alam, M. Jahangir, Garey, Kevin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380534/
https://www.ncbi.nlm.nih.gov/pubmed/35862742
http://dx.doi.org/10.1128/aac.02244-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380534/
https://www.ncbi.nlm.nih.gov/pubmed/35862742
http://dx.doi.org/10.1128/aac.02244-21

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