Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages

Murine macrophages activated by the Toll-like receptor 4 agonist lipopolysaccharide (LPS) polarize to the M1 type by inducing proinflammatory marker proteins and changing their energy metabolism to increased aerobic glycolysis and reduced respiration. We here show that the aliphatic isothiocyanate s...

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Detalles Bibliográficos
Autores principales: Bahiraii, Sheyda, Brenner, Martin, Yan, Fangfang, Weckwerth, Wolfram, Heiss, Elke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380596/
https://www.ncbi.nlm.nih.gov/pubmed/35983049
http://dx.doi.org/10.3389/fimmu.2022.935692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380596/
https://www.ncbi.nlm.nih.gov/pubmed/35983049
http://dx.doi.org/10.3389/fimmu.2022.935692

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