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Interplay Between Chemotherapy-Activated Cancer Associated Fibroblasts and Cancer Initiating Cells Expressing CD44v6 Promotes Colon Cancer Resistance

Cancer-initiating cells (CICs) drive colorectal tumor growth by their supportive niches where CICs interact with multiple cell types within the microenvironment, including cancer-associated fibroblasts (CAFs). We investigated the interplay between the CICs and the clinically relevant chemotherapeuti...

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Detalles Bibliográficos
Autores principales: Ghatak, Shibnath, Hascall, Vincent C., Karamanos, Nikos, Markwald, Roger R., Misra, Suniti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380598/
https://www.ncbi.nlm.nih.gov/pubmed/35982950
http://dx.doi.org/10.3389/fonc.2022.906415