Cargando…
Interplay Between Chemotherapy-Activated Cancer Associated Fibroblasts and Cancer Initiating Cells Expressing CD44v6 Promotes Colon Cancer Resistance
Cancer-initiating cells (CICs) drive colorectal tumor growth by their supportive niches where CICs interact with multiple cell types within the microenvironment, including cancer-associated fibroblasts (CAFs). We investigated the interplay between the CICs and the clinically relevant chemotherapeuti...
Autores principales: | Ghatak, Shibnath, Hascall, Vincent C., Karamanos, Nikos, Markwald, Roger R., Misra, Suniti |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380598/ https://www.ncbi.nlm.nih.gov/pubmed/35982950 http://dx.doi.org/10.3389/fonc.2022.906415 |
Ejemplares similares
-
Chemotherapy induces feedback up-regulation of CD44v6 in colorectal cancer initiating cells through β-catenin/MDR1 signaling to sustain chemoresistance
por: Ghatak, Shibnath, et al.
Publicado: (2022) -
FOLFOX Therapy Induces Feedback Upregulation of CD44v6 through YB-1 to Maintain Stemness in Colon Initiating Cells
por: Ghatak, Shibnath, et al.
Publicado: (2021) -
Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer
por: Misra, Suniti, et al.
Publicado: (2015) -
Stromal Hyaluronan Interaction with Epithelial CD44 Variants Promotes Prostate Cancer Invasiveness by Augmenting Expression and Function of Hepatocyte Growth Factor and Androgen Receptor
por: Ghatak, Shibnath, et al.
Publicado: (2010) -
Utilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy Delivery
por: Misra, Suniti, et al.
Publicado: (2015)