Use of Debye–Hückel–Henry charge measurements in early antibody development elucidates effects of non-specific association

The diffusion interaction parameter (k(D)) has been demonstrated to be a high-throughput technique for characterizing interactions between proteins in solution. k(D) reflects both attractive and repulsive interactions, including long-ranged electrostatic repulsions. Here, we plot the mutual diffusio...

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Detalles Bibliográficos
Autores principales: Laber, Joshua R, Laue, Thomas M, Filoti, Dana I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380711/
https://www.ncbi.nlm.nih.gov/pubmed/35983303
http://dx.doi.org/10.1093/abt/tbac018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380711/
https://www.ncbi.nlm.nih.gov/pubmed/35983303
http://dx.doi.org/10.1093/abt/tbac018

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