Cargando…
Use of Debye–Hückel–Henry charge measurements in early antibody development elucidates effects of non-specific association
The diffusion interaction parameter (k(D)) has been demonstrated to be a high-throughput technique for characterizing interactions between proteins in solution. k(D) reflects both attractive and repulsive interactions, including long-ranged electrostatic repulsions. Here, we plot the mutual diffusio...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380711/ https://www.ncbi.nlm.nih.gov/pubmed/35983303 http://dx.doi.org/10.1093/abt/tbac018 |