A single natural RNA modification can destabilize a U•A-T-rich RNA•DNA-DNA triple helix

Recent studies suggest noncoding RNAs interact with genomic DNA, forming RNA•DNA-DNA triple helices, as a mechanism to regulate transcription. One way cells could regulate the formation of these triple helices is through RNA modifications. With over 140 naturally occurring RNA modifications, we hypo...

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Detalles Bibliográficos
Autores principales: Kunkler, Charlotte N., Schiefelbein, Grace E., O'Leary, Nathan J., McCown, Phillip J., Brown, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380742/
https://www.ncbi.nlm.nih.gov/pubmed/35820700
http://dx.doi.org/10.1261/rna.079244.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380742/
https://www.ncbi.nlm.nih.gov/pubmed/35820700
http://dx.doi.org/10.1261/rna.079244.122

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