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Biological solution conditions and flanking sequence modulate LLPS of RNA G-quadruplex structures

Guanine-rich regions of DNA or RNA can form structures with two or more consecutive G-quartets called G-quadruplexes (GQ). Recent studies reveal the potential for these structures to aggregate in vitro. Here, we report effects of in vivo concentrations of additives—amino acids, nucleotides, and crow...

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Detalles Bibliográficos
Autores principales: Williams, Allison M., Dickson, Taylor M., Lagoa-Miguel, Claudia A., Bevilacqua, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380743/
https://www.ncbi.nlm.nih.gov/pubmed/35760522
http://dx.doi.org/10.1261/rna.079196.122