A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation

The DExD/H-box RNA helicase DHX34 is a nonsense-mediated decay (NMD) factor that together with core NMD factors coregulates NMD targets in nematodes and in vertebrates. Here, we show that DHX34 is also associated with the human spliceosomal catalytic C complex. Mapping of DHX34 endogenous binding si...

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Detalles Bibliográficos
Autores principales: Hug, Nele, Aitken, Stuart, Longman, Dasa, Raab, Michaela, Armes, Hannah, Mann, Abigail R., Rio-Machin, Ana, Fitzgibbon, Jude, Rouault-Pierre, Kevin, Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380745/
https://www.ncbi.nlm.nih.gov/pubmed/35768279
http://dx.doi.org/10.1261/rna.079277.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380745/
https://www.ncbi.nlm.nih.gov/pubmed/35768279
http://dx.doi.org/10.1261/rna.079277.122

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