Target Specific Uptake of a Newly Synthesized Radiolabeled 5α-Reductase Inhibitor “Tc-99m-17-Oxo-17a-Aza-D-Homo-5-Androsten-3β-yl Phenoxyacetate (Tc-99m-17a-Aza Steroid)” in Rat Prostatic Neoplastic Lesions

OBJECTIVE: Considering the 5α-reductase (5AR) inhibitory activity of the oximes and the importance of the ester group in increasing the anti-androgenic property, we reasoned to synthesize a compound having a lactam group in ring D and an ester group at the 3 β position of the androsterone nucleus. T...

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Detalles Bibliográficos
Autores principales: Jan, Gowsia, Bhat, Swati, Chauhan, Monika, Dhawan, Devinder Kumar, Dhingra, Neelima, Chadha, Vijayta Dani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380797/
https://www.ncbi.nlm.nih.gov/pubmed/35982808
http://dx.doi.org/10.4103/ijnm.ijnm_128_21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380797/
https://www.ncbi.nlm.nih.gov/pubmed/35982808
http://dx.doi.org/10.4103/ijnm.ijnm_128_21

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