Cargando…

Target Specific Uptake of a Newly Synthesized Radiolabeled 5α-Reductase Inhibitor “Tc-99m-17-Oxo-17a-Aza-D-Homo-5-Androsten-3β-yl Phenoxyacetate (Tc-99m-17a-Aza Steroid)” in Rat Prostatic Neoplastic Lesions

OBJECTIVE: Considering the 5α-reductase (5AR) inhibitory activity of the oximes and the importance of the ester group in increasing the anti-androgenic property, we reasoned to synthesize a compound having a lactam group in ring D and an ester group at the 3 β position of the androsterone nucleus. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jan, Gowsia, Bhat, Swati, Chauhan, Monika, Dhawan, Devinder Kumar, Dhingra, Neelima, Chadha, Vijayta Dani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380797/ https://www.ncbi.nlm.nih.gov/pubmed/35982808 http://dx.doi.org/10.4103/ijnm.ijnm_128_21

Ejemplares similares

(99m)Tc-Radiolabeled TPGS Nanomicelles Outperform (99m)Tc-Sestamibi as Breast Cancer Imaging Agent
por: Tesan, Fiorella C., et al.
Publicado: (2019)

Comparison of [(99m)Tc]Tc-tilmanocept with [(99m)Tc]Tc-sulphur colloids and [(99m)Tc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head
por: Ooms, Mark, et al.
Publicado: (2022)

Physicochemical and Biological Study of (99m)Tc and (68)Ga Radiolabelled Ciprofloxacin and Evaluation of [(99m)Tc]Tc-CIP as Potential Diagnostic Radiopharmaceutical for Diabetic Foot Syndrome Imaging
por: Koźmiński, Przemysław, et al.
Publicado: (2021)

(99m)Tc-radiolabeled Levofloxacin and micelles as infection and inflammation imaging agents
por: Silindir-Gunay, Mine, et al.
Publicado: (2020)

Clinical usefulness of (99m)Tc-HYNIC-TOC, (99m)Tc(V)-DMSA, and (99m)Tc-MIBI SPECT in the evaluation of pituitary adenomas
por: Vukomanovic, Vladimir R., et al.
Publicado: (2019)

Radiolabeling and Biological Evaluation of Novel (99m)Tc-Nitrido and (99m)Tc-Oxo Complexes with 4-Methoxy-(L)-Phenylalanine Dithiocarbamate for Tumor Imaging
por: Yin, Guangxing, et al.
Publicado: (2022)

Pharmacokinetics of the phosphatidylserine tracers (99m)Tc-lactadherin and (99m)Tc-annexin V in pigs
por: Poulsen, Runa H, et al.
Publicado: (2013)

Head to head comparison of [(99m)Tc]Tc(CO)(3)(NTA) and [(99m)Tc]Tc-MAG3 in patients with suspected obstruction
por: Taylor, Andrew T., et al.
Publicado: (2021)

Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using (99m)Tc-HMPAO
por: Hwang, Do Won, et al.
Publicado: (2015)

(99m)Tc-radiolabeled GE11-modified peptide for ovarian tumor targeting
por: Rahmanian, Najmeh, et al.
Publicado: (2017)

[(99m)Tc]Technetium-Labeled Niosomes: Radiolabeling, Quality Control, and In Vitro Evaluation
por: Ekinci, Meliha, et al.
Publicado: (2023)

Comparing (99m)Tc-PSMA to (99m)Tc-MDP in Prostate Cancer Staging of the Skeletal System
por: Kabunda, Joseph, et al.
Publicado: (2021)

Comparison of (99m)Tc-N-DBODC5 and (99m)Tc-MIBI of Myocardial Perfusion Imaging for Diagnosis of Coronary Artery Disease
por: Ma, Haiyan, et al.
Publicado: (2013)

Sentinel lymph node detection in oral cancer: a within-patient comparison between [(99m)Tc]Tc-tilmanocept and [(99m)Tc]Tc-nanocolloid
por: den Toom, Inne J., et al.
Publicado: (2020)

(99m)Tc-besilesomab (Scintimun®) in peripheral osteomyelitis: comparison with (99m)Tc-labelled white blood cells
por: Richter, Wolf S., et al.
Publicado: (2011)

Study of Binding Kinetics and Specificity of (99m)Tc-SSS-Complex and (99m)Tc-HMPAO to Blood Cells
por: Auletta, S., et al.
Publicado: (2018)

Altered [(99m)Tc]Tc-MDP biodistribution from neutron activation sourced (99)Mo
por: Demeter, Sandor, et al.
Publicado: (2018)

Synthesis, Radiolabeling and Biological Evaluation of (99m)Tc-labeled Deoxyglucose Derivatives for Molecular Imaging
por: Sadeghzadeh, Masoud, et al.
Publicado: (2013)

Chemoinformatic Study and In vitro Bioevaluation of Tc-99m-Labeled N-Acetyl Neuraminic Acid in C6 Glioma Cells: Potential Role as a Radionuclide Imaging Probe
por: Kumar, Ravi Ranjan, et al.
Publicado: (2021)

Anaphylactic Reaction to Tc-99m Macrosalb
por: Schreuder, Nanno, et al.
Publicado: (2019)

Bone turnover markers are correlated with total skeletal uptake of (99m)Tc-methylene diphosphonate ((99m)Tc-MDP)
por: Lenora, Janaka, et al.
Publicado: (2009)

Comparison of Tc-99m pertechnetate images with dual-phase Tc 99m MIBI and SPECT images in primary hyperparathyroidism
por: Sager, Sait, et al.
Publicado: (2014)

Evaluation of interobserver variability of parenchymal phase of Tc-99m mercaptoacetyltriglycine and Tc-99m dimercaptosuccinic acid renal scintigraphy
por: Erdoğan, Zeynep, et al.
Publicado: (2014)

Comparison of [(99m)Tc]Tilmanocept and Filtered [(99m)Tc]Sulfur Colloid for Identification of SLNs in Breast Cancer Patients
por: Baker, Jennifer L., et al.
Publicado: (2014)

Comparison of the Relative Renal Function Calculated with 99mTc-Diethylenetriaminepentaacetic Acid and 99mTc-Dimercaptosuccinic Acid in Children
por: Çelik, Tanju, et al.
Publicado: (2014)

Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer
por: O’Connor, Michael K., et al.
Publicado: (2017)

Regional Liver Disorder with Differences in the Accumulation of (99m)Tc-phytate and (99m)Tc-galactosyl Human Serum Albumin
por: Kotani, Kohei, et al.
Publicado: (2017)

(99m)TcO(4)(-)/(99m)Tc-MIBI dual-tracer scintigraphy for preoperative localization of parathyroid adenomas
por: Huang, Zhongke, et al.
Publicado: (2018)

(95g)Tc and (96g)Tc as alternatives to medical radioisotope (99m)Tc
por: Hayakawa, Takehito, et al.
Publicado: (2018)

(99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
por: Denholt, Charlotte, et al.
Publicado: (2016)

Development of (99m)Tc-radiolabeled nanosilica for targeted detection of HER2-positive breast cancer
por: Rainone, Paolo, et al.
Publicado: (2017)

Synthesis and In Vitro Evaluation of Gold Nanoparticles Functionalized with Thiol Ligands for Robust Radiolabeling with (99m)Tc
por: Apostolopoulou, Adamantia, et al.
Publicado: (2021)

Diagnostic accuracy of [(99m)Tc]Tc-Sestamibi in the assessment of thyroid nodules
por: Yordanova, Anna, et al.
Publicado: (2017)

Imaging Hydrogen Sulfide in Hypoxic Tissue with [(99m)Tc]Tc-Gluconate
por: Kweon, Yongkyoung, et al.
Publicado: (2020)

Poor Tc-99m dimercaptosuccinic acid uptake, re-evaluation with Tc-99m MAG3 scintigraphy in Lowe syndrome
por: Koca, Gokhan, et al.
Publicado: (2011)

Comparison of (99m)Tc-Tetrofosmin and (99m)Tc-Sestamibi Uptake in Glioma Cell Lines: The Role of P-Glycoprotein Expression
por: Alexiou, George A., et al.
Publicado: (2014)

Tc-99m Ethylenedicysteine and Tc-99m Dimercaptosuccinic Acid Scintigraphy-Comparison of the Two for Detection of Scarring and Differential Cortical Function
por: Dharmalingam, Anitha, et al.
Publicado: (2017)

Comparative research on (99m)Tc-Rituximab and (99m)Tc-sulfur colloid in sentinel lymph node imaging of breast cancer
por: Zhang, Jing-Jie, et al.
Publicado: (2019)

Magnesium-Molybate Compounds as Matrix for (99)Mo/(99m)Tc Generators
por: Monroy-Guzman, Fabiola, et al.
Publicado: (2011)

Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO
por: de Vries, Erik F. J., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_gr2rjaa8kckh0gq0m3ing8db8c