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Branching Copy-Number Evolution and Parallel Immune Profiles across the Regional Tumor Space of Resected Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal disease. The only option for curative treatment is resection of the tumor followed by standard adjuvant chemotherapy. Yet, early relapse due to chemoresistance is almost inevitable. Herein, we delineated the genetic intratumor heterogen...

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Detalles Bibliográficos
Autores principales: Petersson, Alexandra, Andersson, Natalie, Hau, Sofie Olsson, Eberhard, Jakob, Karlsson, Jenny, Chattopadhyay, Subhayan, Valind, Anders, Elebro, Jacob, Nodin, Björn, Leandersson, Karin, Gisselsson, David, Jirström, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381114/
https://www.ncbi.nlm.nih.gov/pubmed/35149544
http://dx.doi.org/10.1158/1541-7786.MCR-21-0986