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Increased proportion of follicular helper T cells is associated with B cell activation and disease severity in IgA nephropathy

IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by glomerular deposition of IgA immune complexes, mainly produced by B cells under the regulation of CD4(+)T cells. However, the alterations of specific CD4(+)T cell subsets and the mechanism of B cells activation in...

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Detalles Bibliográficos
Autores principales: Du, Wanshan, Gao, Cai-Yue, You, Xing, Li, Liang, Zhao, Zhi-Bin, Fang, Mengting, Ye, Zhiming, Si, Meijun, Lian, Zhe-Xiong, Yu, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381139/
https://www.ncbi.nlm.nih.gov/pubmed/35983053
http://dx.doi.org/10.3389/fimmu.2022.901465