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Increased proportion of follicular helper T cells is associated with B cell activation and disease severity in IgA nephropathy
IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by glomerular deposition of IgA immune complexes, mainly produced by B cells under the regulation of CD4(+)T cells. However, the alterations of specific CD4(+)T cell subsets and the mechanism of B cells activation in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381139/ https://www.ncbi.nlm.nih.gov/pubmed/35983053 http://dx.doi.org/10.3389/fimmu.2022.901465 |