Cryo-EM structures of prion protein filaments from Gerstmann–Sträussler–Scheinker disease

Prion protein (PrP) aggregation and formation of PrP amyloid (APrP) are central events in the pathogenesis of prion diseases. In the dominantly inherited prion protein amyloidosis known as Gerstmann–Sträussler–Scheinker (GSS) disease, plaques made of PrP amyloid are present throughout the brain. The...

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Detalles Bibliográficos
Autores principales: Hallinan, Grace I., Ozcan, Kadir A., Hoq, Md Rejaul, Cracco, Laura, Vago, Frank S., Bharath, Sakshibeedu R., Li, Daoyi, Jacobsen, Max, Doud, Emma H., Mosley, Amber L., Fernandez, Anllely, Garringer, Holly J., Jiang, Wen, Ghetti, Bernardino, Vidal, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381446/
https://www.ncbi.nlm.nih.gov/pubmed/35819518
http://dx.doi.org/10.1007/s00401-022-02461-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381446/
https://www.ncbi.nlm.nih.gov/pubmed/35819518
http://dx.doi.org/10.1007/s00401-022-02461-0

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