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Peripheral N-methyl-d-aspartate receptor activation contributes to monosodium glutamate-induced headache but not nausea behaviours in rats

Monosodium glutamate induces behaviors thought to reflect headache and nausea in rats. We explored the effects of the N-methyl-d-aspartate receptor antagonist (2R)-amino-5-phosphonovaleric acid, the inotropic glutamate receptor antagonist kynurenic acid, and the CGRP receptor antagonist olcegepant,...

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Detalles Bibliográficos
Autores principales: Benbow, Tarique, Teja, Felisha, Sheikhi, Afrooz, Exposto, Fernando G., Svensson, Peter, Cairns, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381496/
https://www.ncbi.nlm.nih.gov/pubmed/35974090
http://dx.doi.org/10.1038/s41598-022-18290-w