Pinocembrin suppresses oxidized low-density lipoprotein-triggered NLRP3 inflammasome/GSDMD-mediated endothelial cell pyroptosis through an Nrf2-dependent signaling pathway

Pinocembrin (Pin) has been confirmed to exert anti-inflammatory and antiatherosclerotic effects. Here we have explored whether and how Pin would protect vascular endothelial cells against pyroptosis elicited by the exposure to oxidized low density lipoprotein (oxLDL). Our results showed that Pin pre...

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Detalles Bibliográficos
Autores principales: Wang, Tong, Tian, Hua, Pan, Tianqi, Yao, Shutong, Yu, Huayun, Wu, Yumei, Wang, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381505/
https://www.ncbi.nlm.nih.gov/pubmed/35974041
http://dx.doi.org/10.1038/s41598-022-18297-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381505/
https://www.ncbi.nlm.nih.gov/pubmed/35974041
http://dx.doi.org/10.1038/s41598-022-18297-3

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