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CRELD2 is a novel modulator of calcium release and calcineurin-NFAT signalling during osteoclast differentiation

Cysteine rich with epidermal growth factor (EGF)-like domains 2 (CRELD2) is an endoplasmic reticulum (ER) resident chaperone protein with calcium binding properties. CRELD2 is an ER-stress regulated gene that has been implicated in the pathogenesis of skeletal dysplasias and has been shown to play a...

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Detalles Bibliográficos
Autores principales: Duxfield, Adam, Munkley, Jennifer, Briggs, Michael D., Dennis, Ella P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381524/
https://www.ncbi.nlm.nih.gov/pubmed/35974042
http://dx.doi.org/10.1038/s41598-022-17347-0