USP21 promotes self-renewal and tumorigenicity of mesenchymal glioblastoma stem cells by deubiquitinating and stabilizing FOXD1

Recent studies suggest that Forkhead box D1 (FOXD1) plays an indispensable role in maintaining the mesenchymal (MES) properties of glioblastoma (GBM) stem cells (GSCs). Thus, understanding the mechanisms that control FOXD1 protein expression is critical for guiding GBM treatment, particularly in pat...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qixiang, Chen, Zhengxin, Tang, Qikai, Wang, Zhangjie, Lu, Jiacheng, You, Yongping, Wang, Huibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381540/
https://www.ncbi.nlm.nih.gov/pubmed/35974001
http://dx.doi.org/10.1038/s41419-022-05163-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381540/
https://www.ncbi.nlm.nih.gov/pubmed/35974001
http://dx.doi.org/10.1038/s41419-022-05163-3

Ejemplares similares