Gene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy

PURPOSE: Preoperative (neoadjuvant) chemoradiotherapy (CRT) and total mesorectal excision is the standard treatment for rectal cancer patients (UICC stage II/III). Up to one-third of patients treated with CRT achieve a pathological complete response (pCR). These patients could be spared from surgery...

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Detalles Bibliográficos
Autores principales: Emons, Georg, Auslander, Noam, Jo, Peter, Kitz, Julia, Azizian, Azadeh, Hu, Yue, Hess, Clemens F., Roedel, Claus, Sax, Ulrich, Salinas, Gabriela, Stroebel, Philipp, Kramer, Frank, Beissbarth, Tim, Grade, Marian, Ghadimi, Michael, Ruppin, Eytan, Ried, Thomas, Gaedcke, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381580/
https://www.ncbi.nlm.nih.gov/pubmed/35597871
http://dx.doi.org/10.1038/s41416-022-01842-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381580/
https://www.ncbi.nlm.nih.gov/pubmed/35597871
http://dx.doi.org/10.1038/s41416-022-01842-2

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