DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2

Metastasis is a major cause of colorectal cancer (CRC) mortality, but its molecular mechanisms are still not fully understood. Here, we show that upregulated DDX39B correlates with liver metastases and aggressive phenotypes in CRC. DDX39B is an independent prognostic factor associated with poor clin...

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Detalles Bibliográficos
Autores principales: Zhao, Gang, Yuan, Hang, Li, Qin, Zhang, Jie, Guo, Yafei, Feng, Tianyu, Gu, Rui, Ou, Deqiong, Li, Siqi, Li, Kai, Lin, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381590/
https://www.ncbi.nlm.nih.gov/pubmed/35973989
http://dx.doi.org/10.1038/s41392-022-01096-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381590/
https://www.ncbi.nlm.nih.gov/pubmed/35973989
http://dx.doi.org/10.1038/s41392-022-01096-7

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