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Salvianolic acid B inhibits RAW264.7 cell polarization towards the M1 phenotype by inhibiting NF-κB and Akt/mTOR pathway activation

M1 macrophages secrete a large number of proinflammatory factors and promote the expansion of atherosclerotic plaques and processes. Salvianolic acid B (Sal B) exerts anti-inflammatory, antitumor and other effects, but no study has addressed whether Sal B can regulate the polarization of macrophages...

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Detalles Bibliográficos
Autores principales: Zou, Tao, Gao, Shan, Yu, Zhaolan, Zhang, Fuyong, Yao, Lan, Xu, Mengyao, Li, Junxin, Wu, Zhigui, Huang, Yilan, Wang, Shurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381594/
https://www.ncbi.nlm.nih.gov/pubmed/35974091
http://dx.doi.org/10.1038/s41598-022-18246-0