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Salvianolic acid B inhibits RAW264.7 cell polarization towards the M1 phenotype by inhibiting NF-κB and Akt/mTOR pathway activation
M1 macrophages secrete a large number of proinflammatory factors and promote the expansion of atherosclerotic plaques and processes. Salvianolic acid B (Sal B) exerts anti-inflammatory, antitumor and other effects, but no study has addressed whether Sal B can regulate the polarization of macrophages...
Autores principales: | Zou, Tao, Gao, Shan, Yu, Zhaolan, Zhang, Fuyong, Yao, Lan, Xu, Mengyao, Li, Junxin, Wu, Zhigui, Huang, Yilan, Wang, Shurong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381594/ https://www.ncbi.nlm.nih.gov/pubmed/35974091 http://dx.doi.org/10.1038/s41598-022-18246-0 |
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