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Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention

Blood-based (BB) biomarkers for Aβ and tau can indicate pathological processes in the brain, in the early pathological, even pre-symptomatic stages in Alzheimer’s disease. However, the relation between BB biomarkers and AD-related processes in the brain in the earliest pre-pathology stage before amy...

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Detalles Bibliográficos
Autores principales: Botella Lucena, Pablo, Vanherle, Sarah, Lodder, Chritica, Gutiérrez de Ravé, Manuel, Stancu, Ilie-Cosmin, Lambrichts, Ivo, Vangheluwe, Riet, Bruffaerts, Rose, Dewachter, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381631/
https://www.ncbi.nlm.nih.gov/pubmed/35796870
http://dx.doi.org/10.1007/s00401-022-02458-9