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Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention
Blood-based (BB) biomarkers for Aβ and tau can indicate pathological processes in the brain, in the early pathological, even pre-symptomatic stages in Alzheimer’s disease. However, the relation between BB biomarkers and AD-related processes in the brain in the earliest pre-pathology stage before amy...
Autores principales: | Botella Lucena, Pablo, Vanherle, Sarah, Lodder, Chritica, Gutiérrez de Ravé, Manuel, Stancu, Ilie-Cosmin, Lambrichts, Ivo, Vangheluwe, Riet, Bruffaerts, Rose, Dewachter, Ilse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381631/ https://www.ncbi.nlm.nih.gov/pubmed/35796870 http://dx.doi.org/10.1007/s00401-022-02458-9 |
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