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Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11)C]UCB‐J

INTRODUCTION: For 30 years synapse loss has been referred to as the major pathological correlate of cognitive impairment in Alzheimer's disease (AD). However, this statement is based on remarkably few patients studied by autopsy or biopsy. With the recent advent of synaptic vesicle glycoprotein...

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Detalles Bibliográficos
Autores principales: Mecca, Adam P., O'Dell, Ryan S., Sharp, Emily S., Banks, Emmie R., Bartlett, Hugh H., Zhao, Wenzhen, Lipior, Sylwia, Diepenbrock, Nina G., Chen, Ming‐Kai, Naganawa, Mika, Toyonaga, Takuya, Nabulsi, Nabeel B., Vander Wyk, Brent C., Arnsten, Amy F. T., Huang, Yiyun, Carson, Richard E., van Dyck, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381645/
https://www.ncbi.nlm.nih.gov/pubmed/35174954
http://dx.doi.org/10.1002/alz.12582