Transient reduction in dendritic spine density in brain-specific profilin1 mutant mice is associated with behavioral deficits

Actin filaments form the backbone of dendritic spines, the postsynaptic compartment of most excitatory synapses in the brain. Spine density changes affect brain function, and postsynaptic actin defects have been implicated in various neuropathies. It is mandatory to identify the actin regulators tha...

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Detalles Bibliográficos
Autores principales: Sungur, A. Özge, Zeitouny, Caroline, Gabele, Lea, Metz, Isabell, Wöhr, Markus, Michaelsen-Preusse, Kristin, Rust, Marco B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381693/
https://www.ncbi.nlm.nih.gov/pubmed/35992199
http://dx.doi.org/10.3389/fnmol.2022.952782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381693/
https://www.ncbi.nlm.nih.gov/pubmed/35992199
http://dx.doi.org/10.3389/fnmol.2022.952782

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