Generation of synthetic antibody fragments with optimal complementarity determining region lengths for Notch-1 recognition

Synthetic antibodies have been engineered against a wide variety of antigens with desirable biophysical, biochemical, and pharmacological properties. Here, we describe the generation and characterization of synthetic antigen-binding fragments (Fabs) against Notch-1. Three single-framework synthetic...

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Detalles Bibliográficos
Autores principales: Maruthachalam, Bharathikumar Vellalore, Barreto, Kris, Hogan, Daniel, Kusalik, Anthony, Geyer, Clarence Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381698/
https://www.ncbi.nlm.nih.gov/pubmed/35992693
http://dx.doi.org/10.3389/fmicb.2022.931307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381698/
https://www.ncbi.nlm.nih.gov/pubmed/35992693
http://dx.doi.org/10.3389/fmicb.2022.931307

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