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Melatonin prevents cyclophosphamide-induced primordial follicle loss by inhibiting ovarian granulosa cell apoptosis and maintaining AMH expression

Cyclophosphaty -45mide (Cyc) chemotherapy in young female cancer patients is associated with an increased risk of premature ovarian insufficiency (POI). This study was designed to investigate the protective role of melatonin (Mel) as an adjuvant against Cyc-induced POI. Female mice received a single...

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Detalles Bibliográficos
Autores principales: Feng, Juan, Ma, Wen-Wen, Li, Hui-Xia, Pei, Xiu-Ying, Deng, Shou-Long, Jia, Hua, Ma, Wen-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381702/
https://www.ncbi.nlm.nih.gov/pubmed/35992124
http://dx.doi.org/10.3389/fendo.2022.895095