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Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach

Visceral leishmaniasis (VL), caused by Leishmania infantum, is an oft-fatal neglected tropical disease. In the absence of an effective vaccine, the control of leishmaniasis relies exclusively on chemotherapy. Due to the lack of established molecular/genetic markers denoting parasite resistance, clin...

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Detalles Bibliográficos
Autores principales: Ibarra-Meneses, Ana Victoria, Corbeil, Audrey, Wagner, Victoria, Beaudry, Francis, do Monte-Neto, Rubens L., Fernandez-Prada, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381709/
https://www.ncbi.nlm.nih.gov/pubmed/35992178
http://dx.doi.org/10.3389/fcimb.2022.954144