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TXN inhibitor impedes radioresistance of colorectal cancer cells with decreased ALDH1L2 expression via TXN/NF-κB signaling pathway

BACKGROUND: Colorectal cancer (CRC) is prevalent worldwide and is often challenged by treatment failure and recurrence due to resistance to radiotherapy. Here, we aimed to identify the elusive underlying molecular mechanisms of radioresistance in CRC. METHODS: Weighted gene co-expression network ana...

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Detalles Bibliográficos
Autores principales: Yu, Lu, Guo, Qiqing, Luo, Ziqian, Wang, Yongjia, Weng, Jiawen, Chen, Yuchuan, Liang, Weijie, Li, Yiyi, Zhang, Yuqin, Chen, Keli, Chen, Zhenhui, Ding, Yi, Zhang, Yaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381770/
https://www.ncbi.nlm.nih.gov/pubmed/35597868
http://dx.doi.org/10.1038/s41416-022-01835-1