Mapping the dynamics of insulin-responsive pathways in the blood–brain barrier endothelium using time-series transcriptomics data

Critical functions of the blood–brain barrier (BBB), including cerebral blood flow, energy metabolism, and immunomodulation, are regulated by insulin signaling pathways. Therefore, endothelial insulin resistance could lead to BBB dysfunction, which is associated with neurodegenerative diseases such...

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Detalles Bibliográficos
Autores principales: Wang, Zengtao, Tang, Xiaojia, Swaminathan, Suresh K., Kandimalla, Karunya K., Kalari, Krishna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381797/
https://www.ncbi.nlm.nih.gov/pubmed/35974022
http://dx.doi.org/10.1038/s41540-022-00235-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381797/
https://www.ncbi.nlm.nih.gov/pubmed/35974022
http://dx.doi.org/10.1038/s41540-022-00235-8

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