Fluorine impairs carboxylesterase 1-mediated hydrolysis of T-2 toxin and increases its chondrocyte toxicity

BACKGROUND: T-2 toxin is recognized as one of the high-risk environmental factors for etiology and pathogenesis of Kashin-Beck disease (KBD). Previous evidence indicates decreased serum fluorine level in KBD patients. However, whether fluoride could regulate carboxylesterase 1 (CES1)-mediated T-2 to...

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Detalles Bibliográficos
Autores principales: Jia, Yumeng, Shi, Sirong, Cheng, Bolun, Cheng, Shiqiang, Liu, Li, Meng, Peilin, Yang, Xuena, Chu, Xiaoge, Wen, Yan, Zhang, Feng, Guo, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381868/
https://www.ncbi.nlm.nih.gov/pubmed/35990316
http://dx.doi.org/10.3389/fnut.2022.935112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381868/
https://www.ncbi.nlm.nih.gov/pubmed/35990316
http://dx.doi.org/10.3389/fnut.2022.935112

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