Population pharmacokinetic model for once‐daily intravenous busulfan in pediatric subjects describing time‐associated clearance

This study aimed to characterize the population pharmacokinetics (PK) of busulfan focusing on how busulfan clearance (CL) changes over time during once‐daily administration and assess different methods for measuring busulfan exposure and the ability to achieve target cumulative exposure under differ...

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Detalles Bibliográficos
Autores principales: Lawson, Rachael, Staatz, Christine E., Fraser, Christopher J., Ramachandran, Shanti, Teague, Lochie, Mitchell, Richard, O'Brien, Tracey, Hennig, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381908/
https://www.ncbi.nlm.nih.gov/pubmed/35611997
http://dx.doi.org/10.1002/psp4.12809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381908/
https://www.ncbi.nlm.nih.gov/pubmed/35611997
http://dx.doi.org/10.1002/psp4.12809

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