Structural-Guided Identification of Small Molecule Inhibitor of UHRF1 Methyltransferase Activity

Ubiquitin-like containing plant homeodomain Ring Finger 1 (UHRF1) protein is recognized as a cell-cycle-regulated multidomain protein. UHRF1 importantly manifests the maintenance of DNA methylation mediated by the interaction between its SRA (SET and RING associated) domain and DNA methyltransferase...

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Detalles Bibliográficos
Autores principales: Awal, Md Abdul, Nur, Suza Mohammad, Al Khalaf, Ali Khalaf, Rehan, Mohd, Ahmad, Aamir, Hosawi, Salman Bakr I., Choudhry, Hani, Khan, Mohammad Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382028/
https://www.ncbi.nlm.nih.gov/pubmed/35991572
http://dx.doi.org/10.3389/fgene.2022.928884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382028/
https://www.ncbi.nlm.nih.gov/pubmed/35991572
http://dx.doi.org/10.3389/fgene.2022.928884

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