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Challenges in describing the conformation and dynamics of proteins with ambiguous behavior
Traditionally, our understanding of how proteins operate and how evolution shapes them is based on two main data sources: the overall protein fold and the protein amino acid sequence. However, a significant part of the proteome shows highly dynamic and/or structurally ambiguous behavior, which canno...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382080/ https://www.ncbi.nlm.nih.gov/pubmed/35992270 http://dx.doi.org/10.3389/fmolb.2022.959956 |