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Challenges in describing the conformation and dynamics of proteins with ambiguous behavior

Traditionally, our understanding of how proteins operate and how evolution shapes them is based on two main data sources: the overall protein fold and the protein amino acid sequence. However, a significant part of the proteome shows highly dynamic and/or structurally ambiguous behavior, which canno...

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Detalles Bibliográficos
Autores principales: Roca-Martinez, Joel, Lazar, Tamas, Gavalda-Garcia, Jose, Bickel, David, Pancsa, Rita, Dixit, Bhawna, Tzavella, Konstantina, Ramasamy, Pathmanaban, Sanchez-Fornaris, Maite, Grau, Isel, Vranken, Wim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382080/
https://www.ncbi.nlm.nih.gov/pubmed/35992270
http://dx.doi.org/10.3389/fmolb.2022.959956