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Ataxia telangiectasia mutated: The potential negative regulator in platelet-derived growth factor-BB promoted proliferation of pulmonary arterial smooth muscle cells

OBJECTIVE: To study the role of ataxia telangiectasia mutated (ATM) in the platelet-derived growth factor (PDGF)-BB-induced proliferation of pulmonary arterial smooth muscle cells (PASMCs) through reactive oxygen species (ROS) formation. METHODS: Primary cultures of PASMCs were treated with differen...

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Detalles Bibliográficos
Autores principales: Qin, Chaoyi, Zan, Yiheng, Xie, Liang, Liu, Hanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382100/
https://www.ncbi.nlm.nih.gov/pubmed/35990964
http://dx.doi.org/10.3389/fcvm.2022.942251