Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRα signalling in cerebellar development

Formation of the mouse cerebellum is initiated in the embryo and continues for a few weeks after birth. Double-mutant mice lacking platelet-derived growth factor C (PDGF-C) and that are heterozygous for platelet-derived growth factor receptor alpha (Pdgfc(-/-); Pdgfra(GFP/+)) develop cerebellar hypo...

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Detalles Bibliográficos
Autores principales: Gillnäs, Sara, Gallini, Radiosa, He, Liqun, Betsholtz, Christer, Andrae, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382116/
https://www.ncbi.nlm.nih.gov/pubmed/35876806
http://dx.doi.org/10.1242/bio.059431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382116/
https://www.ncbi.nlm.nih.gov/pubmed/35876806
http://dx.doi.org/10.1242/bio.059431

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