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A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation

Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis. Following transient physical or pharmacological manipulations of embryo size, pre-gastrulation mouse embryos show r...

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Detalles Bibliográficos
Autores principales: Chen, Tingxu, Alcorn, Heather, Devbhandari, Sujan, Remus, Dirk, Lacy, Elizabeth, Huangfu, Danwei, Anderson, Kathryn V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382117/
https://www.ncbi.nlm.nih.gov/pubmed/35876795
http://dx.doi.org/10.1242/bio.059307