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A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation
Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis. Following transient physical or pharmacological manipulations of embryo size, pre-gastrulation mouse embryos show r...
Autores principales: | Chen, Tingxu, Alcorn, Heather, Devbhandari, Sujan, Remus, Dirk, Lacy, Elizabeth, Huangfu, Danwei, Anderson, Kathryn V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9382117/ https://www.ncbi.nlm.nih.gov/pubmed/35876795 http://dx.doi.org/10.1242/bio.059307 |
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